Showing posts with label Science. Show all posts
Showing posts with label Science. Show all posts

Oct 28, 2023

Interstellar Visitor for Eons

"I think it's going to be inconclusive, if not impossible to demonstrate conclusively," one physicist said of the possible interstellar comet.

By Becky Ferreira

A comet that may have come from interstellar space just made its latest dramatic swing around the Sun, an encounter that was imaged in mesmerizing detail by a space observatory. 

The origins of Comet 96P/Machholz (96P) have puzzled scientists for decades since its discovery. It is a four-mile-wide “sungrazer” object with a host of weird properties that suggest it may be an interloper from another star system. For instance, 96P’s composition is extremely unique and its orbit is highly tilted, causing it to pass closer to the Sun than almost any other comet.

These features, among others, suggest that 96P may have been rerouted into our solar system by a chance encounter with Jupiter after its voyage across interstellar space. In an ironic twist, however, the comet's interactions with Jupiter have obscured its backstory and raised the possibility that its oddities could simply point to an origin in an unusual part of our own solar system, or as part of a local celestial body that broke apart. 

“Because of its interactions with Jupiter, I think it's going to be inconclusive, if not impossible to demonstrate conclusively, that it came from another solar system because that dynamical history is lost,” said Matthew Knight, a professor in the physics department at United States Naval Academy who has published research about 96P, in a call with Motherboard.

For the time being, we’ll have to make do with the incredible images of the comet’s closest passes around the Sun, known as the “perihelions” of its five-year orbit. The comet completed its most recent perihelion on Tuesday, when it passed about three times closer to the Sun than Mercury. The approach was observed by the Solar and Heliospheric Observatory (SOHO), a joint space mission between NASA and the European Space Agency, which has watched 96P’s perihelions since it was first launched 1995.  

96P was first discovered by the amateur astronomer Donald Machholz, who spotted it with binoculars from California in 1986. More recent observations have revealed that the object is bizarrely depleted in common materials, like carbon and cyanogen, and does not appear to possess the dusty atmosphere, or “coma,” seen around other comets in the solar system. 

These features hint that the comet might be a completely stripped down nucleus with a “primordial and possibly…interstellar origin,” according to a 2019 study in Astrophysical Journal, co-authored by Knight, that was based on observations of 96P’s 2017 perihelion.

Those observations also revealed that the comet’s colors appear similar to those of ‘Oumuamua, which was the first unambiguous interstellar object ever seen in the solar system. ‘Oumuamua hurtled through our system in late 2017, and also displayed weird features and motions that led to some speculation that it was a piece of alien technology, though most scientists think it had a natural origin.

The intriguing similarities “between the nucleus of 96P and 'Oumuamua might strengthen the argument for 96P having had an interstellar origin” meaning that its “surface properties were acquired during millions of years of cosmic-ray bombardment between systems, rather than having been due to evolution in our solar system,” according to the 2019 study. 

Ultimately, though, Knight said the mystery of 96P’s origin may never be solved, in part because it is not the easiest object to study. Its angled orbit never takes it particularly close to Earth, and its lack of activity makes it tricky to observe except when it's close to perihelion. Though space observatories such as SOHO can study it, many of the comet’s secrets, including its origin, are still locked away.

Even if we were to launch an intercept mission to the comet, we might not be able to answer tantalizing questions about the comet’s past.

“I think [an intercept mission] can tell you that it's very strange,” Knight said of 96P. “I don't think it would conclusively tell you if it was interstellar, or not. But it would certainly be fascinating to go and see this object. I'd love to see it up close.”

Regardless of whether we learn more about the backstory of this elusive comet, scientists are likely to spot many more interstellar objects in the coming years, following the discovery of the first known interstellar comet, called 2I/Borisov, and the first known meteors that likely traveled from another star system before hitting Earth. Many more of these cosmic interlopers are expected to be spotted by next-generation telescopes, such as the Vera C. Rubin Observatory in Chile.

“Right now, we have such a small number of statistics that things are all over the map,” Knight said. “Borisov is kind of what we expected, but ‘Oumuamua is just so funky that it threw us off our game, so to speak.” 

“The work that came out of ‘Oumuamua in particular pegged the number that we might find in the Vera Rubin era at probably about one a year,” he concluded. “I think it'll be really fascinating to see—as interstellar comets number three, four, or five, and so on, come in—where they're falling in that spectrum between crazy and sort of ho-hum.” -VICE 

Oct 14, 2023

Cancer Rates Increase In Younger individuals

A recent study published in BMJ Oncology has highlighted a concerning trend: the rise of cancer among younger people. While cancer has traditionally been more prevalent among older individuals, the analysis of health data shows a significant increase in early-onset cancer cases in people under the age of 50 over the past three decades.

The study revealed that in 2019, there were 1.82 million new cancer diagnoses and 1.06 million deaths from cancer among individuals under 50 globally. These figures represent a 79% increase in diagnoses and a 28% increase in deaths compared to data from 1990.

The research also identified specific types of cancer that experienced the steepest rise between 1990 and 2019. Early-onset cancers of the windpipe and prostate saw the highest increase, estimated to be 2.28% and 2.23% per year, respectively. Breast cancer, the most common type of cancer worldwide excluding non-melanoma skin cancer, accounted for the largest number of cases and associated deaths among yoThe study further noted that while early-onset cancer rates were a concern globally, the highest rates of new cases in 2019 were observed in wealthy countries in North America, Western Europe, and Australasia. Conversely, lower-income countries in Central Asia, Eastern Europe, and Oceania experienced disproportionately high death rates.

Looking ahead, researchers predict that new early-onset cancer cases and associated deaths will increase by an additional 31% and 21%, respectively, by 2030. Individuals in their 40s are expected to be the most at risk.

The reasons behind the rise in early-onset cancer cases remain largely unknown. Various factors, including genetic predispositions, exposure to viruses, environmental pollutants, lifestyle changes, and screening improvements, could contribute to the increase. The researchers recommend expanding screening programs, particularly for individuals aged 40 to 49, to help mitigate the future burden on healthcare systems.

In 2020, approximately 10 million people died of cancer worldwide, making it responsible for nearly one in every six deaths. The World Health Organization highlights preventable factors such as tobacco use, high body mass index, alcohol consumption, poor diet, and physical inactivity as significant contributors to cancer-related deaths.

While the rise of cancer among younger people is a cause for concern, further research is needed to fully understand the underlying causes and develop effective prevention and treatment strategies.unger people. -The Press Rundown 


How Humidity Affects the Growth of Plants

Everything in an environment affects how a plant grows, thrives and reproduces. When growing plants indoors, climate control is essential to maximize the photosynthetic process. By maintaining optimal relative humidity levels in a greenhouse and other growing environments, you ensure optimal plant transpiration.

The Effects of Humidity on Plants

The relative humidity is the amount of water vapor in the air relative to the maximum amount of water vapor that the air can hold at a certain temperature. If the relative humidity level is 75 percent at 80° F, this means that every kilogram of the air in the respective space contains 75 percent of the maximum amount of water that it can hold for the given temperature.

Relative humidity levels affect when and how plants open the stomata on the undersides of their leaves. Plants use stomata to transpire, or “breathe.” When the weather is warm, a plant may close its stomata to reduce water losses. The stomata also act as a cooling mechanism. When ambient conditions are too warm for a plant and it closes its stomata for too long to conserve water, it has no way to move carbon dioxide and oxygen molecules, slowly causing the plant to suffocate on water vapor and its own transpired gases.

As plants transpire, the humidity around saturates leaves with water vapor. When relative humidity levels are too high or there is a lack of air circulation, a plant cannot make water evaporate (part of the transpiration process) or draw nutrients from the soil. When this occurs for a prolonged period, a plant eventually rots. When surrounded by warm temperatures in low relative humidity levels, transpiration rates in a plant increase, increasing the need for a grower to fertilize it.

The Importance of Climate Control for Plant Growth

As seedlings grow or when a grower propagates plants from leaf or stem cuttings, the young or collected plants automatically close their stomata as a protective measure to prevent water losses. To support cuttings and young plants, growers often use plastic tents or propagation chambers that increase relative humidity levels surrounding the leaves and ensure proper air circulation.

In addition to water and air, plants use light energy for the transpiration process, as it causes liquid water to turn to vapor (evaporation). Greenhouses often maintain relative humidity levels below threshold values during the day and night by controlling the water content in the air to maintain a minimum transpiration rate in plants.

Climate control for plant growth is an essential consideration in regards to pest and disease management. When conditions are too humid, it may promote the growth of mold and bacteria that cause plants to die and crops to fail, as well as conditions like root or crown rot. Humid conditions also invite the presence of pests, such as fungus gnats, whose larva feed on plant roots and thrive in moist soil.

Managing the growth and development of plants involves manipulating a growing environment so light, temperature, and relative humidity levels promote photosynthesis, high yields, and generative growth. Optimal transpiration rates vary by plant type, age, and season, making climate control for plant growth necessary throughout the year. Polygon offers custom-made temporary climate control solutions that create the ideal growing environment by regulating and monitoring temperatures and humidity levels. Talk to a Polygon representative today to learn more about how temporary climate control works in conjunction with greenhouse lighting and irrigation systems to optimize plant growth.  -Polygongroup


Marijuana

A new federally funded study has found that marijuana is “significantly” associated with reduced opioid cravings for people using them without a prescription, suggesting that expanding access to legal cannabis could provide more people with a safer substitute.

Researchers at the British Columbia Centre on Substance Use and UCLA surveyed 205 people who use cannabis and opioids without a prescription from December 2019 to November 2021, aiming to test the theory that marijuana represents an effective harm reduction tool amid the overdose crisis.

The study, published in the International Journal of Drug Policy, found that 58 percent of participants reported that their motivation to use marijuana was to reduce opioid cravings. And a multivariable analysis showed that cannabis use “was significantly associated with self-reported reductions in opioid use.”

The researchers said that, to their knowledge, this represents the first study of its kind to specifically investigate “outcomes of intentional cannabis use to manage opioid cravings” among those who are using painkillers that they may be getting from the illicit market, which comes with a risk of obtaining contaminated products.

“These findings indicate that cannabis use to manage opioid cravings is a prevalent motivation for cannabis use among [people who use unregulated opioids] and is associated with self-assessed reductions in opioid use during periods of cannabis use,” the study authors wrote. “Increasing the accessibility of cannabis products for therapeutic use may be a useful supplementary strategy to mitigate exposure to unregulated opioids and associated harm during the ongoing drug toxicity crisis.”

The U.S. National Institutes of Health (NIH) and Canadian Institutes of Health Research (CIHR) provided funding for the study. One of the seven study authors disclosed that he has professorship backed by the cannabis company Canopy Growth to research marijuana science at the University of British Columbia.

This is one of the latest pieces of research in a large pool of scientific literature suggesting that marijuana can serve as a substitute for both legal and illegal substances and prescription drugs.

A study published last month linked medical marijuana use to lower pain levels and reduced dependence on opioids and other prescription medications, for example.

Another study published by the American Medical Association (AMA) in February found that chronic pain patients who received medical marijuana for longer than a month saw significant reductions in prescribed opioids.

AMA also released research showing that about one in three chronic pain patients report using cannabis as a treatment option, and most of that group has used cannabis as a substitute for other pain medications, including opioids.

State-level marijuana legalization is associated with major reductions in prescribing of the opioid codeine specifically, too, according to a study that leveraged data from the federal Drug Enforcement Administration (DEA).

A study that was released last year similarly found that giving people legal access to medical cannabis can help patients reduce their use of opioid painkillers, or cease use altogether, without compromising quality of life.

There’s no deficit of anecdotal reports, data-based studies and observational analyses that have signaled that some people use cannabis as an alternative to traditional pharmaceutical drugs like opioid-based painkillers and sleep medications. -Marijuanamoment 


Sep 23, 2023

Fungus Might Be Taking Over Your Body

By Not Listed

The idea of fungus on your body at all is a gross and unsettling one to have, However, it happens a lot more often than you would realize, and that does not mean you literally have mushrooms growing all over your body. The fact of the matter is there is a variety type of fungi and mushrooms are just one type.

Not to mention, some types of fungi are good for you and necessary for your health. The same goes for bacteria. However, when bad and invading fungi are in the picture, then problems can happen and one of the ones to know about is yeast or candida. You don’t want that in your body. Let’s go over 12 signs that fungus could be taking over your body:

Pneumonia After Being In Agricultural Environments

If you are a farmer and you have been around bird droppings and moldy crops, then you will end up with a cough, sneezing, and a fever. If you are coughing black mucous, then you have fungal pneumonia that can be treated with antifungal drugs. However, you want to be seen by a doctor quickly.

You Crave Sugar And Fermented Foods

If you are
craving sugar or fermented foods, then you have too much candida in your body, and the same goes for having cravings for moldy foods and vinegar. You may have yeast elevated in your bloodstream. And the best thing you can do is to get a blood test done and start detoxing by eating organic and fresh foods. Antibiotics can cause this to happen as well as other drugs such as birth control pills and cortisone.

Fungal Infections In Your Nails

Are you dealing with yellow nails whether they are on your fingers or toes, then you have fungal infections on your nails? That is also the result of yeast in your body going wild. You can get antifungal cream and treatment for it.

Athlete’s Foot

When your feet aren’t cleaned enough, it can grow bacteria as well as fungi getting out of control. Then you will end up with Athlete’s foot which is a fungal infection on your feet that causes plenty of itching and burning sensations. There are plenty of treatments for Athlete’s Foot.

Bloating

If you think that bloating is from your diet, it very well might be, but there are other causes for bloating. And one of the causes for bloating is that you have yeast going wild within your body. That will create plenty of digestive upsets. The thing to do is to get your blood test taken to determine the levels of yeast in your blood. High levels of yeast will contribute to bloating.

Dry Mouth And Halitosis

Do you all of a sudden suffer from dry mouth and halitosis? Then you may have a condition called thrush, especially if you notice white patches on your mouth. That is a yeast infection in your mouth. That can result from a medication you take, and there are treatments for thrush.

Poor Concentration

Are you struggling with concentration as well as brain fog? Is your memory becoming an issue? And this is not something you had to deal with before. That can also be a sign of elevated yeast levels in your blood. A healthy diet free of sugar and simple carbs will help with that.

Psoriasis Or Eczema

You may think skin conditions are related to allergies or dry air, which it can be. However, conditions such as eczema or psoriasis can also be a sign of yeast being out of control in your body. A change in diet and antifungal skin cream will help.

Hives Or Seasonal Allergies

Hives and seasonal allergies happen to many of us, but if you are ending up with these issues suddenly, then that is also a sign that you have too much yeast in your body. If you change your diet to fresh and organic foods free of sugar, then you may see that being the case as the allergies and hives calm.

Mood Swings

You may not think that mood swings are related to too much yeast, but they can be. Especially if you tie your mood swings with a diet high in sugar. If you change your diet to healthy foods, then you will see that your mood swings improve. That would be a yeast connection.

UTI

Do you struggle with urinary tract infections? Even if you keep drinking cranberry juice which is supposed to be good for your bladder? Then it can be due to an overgrowth of yeast. You will want to have your yeast levels checked if you have another UTI to get the appropriate treatment.

Vaginal Or Rectal Infections

If you are ending up with rectal or vaginal (and men can end up with itchiness as well in their groin), then that is a yeast infection. That is caused by medication as well as a poor diet with too much sugar. You will want to get the yeast infection treated and then change your diet.

Fungal infections are more common than you think and they manifest themselves in different ways. However, if you have any of these symptoms, then you likely have fungal infections which means you can be treated. A healthy diet with limited or better yet, free of sugar helps. -World Wide News

Planet Almost Exactly Earth's Size

 By Michelle Starr

We've just found an exoplanet almost exactly the same size as Earth orbiting a tiny star not very far away at all.

It's called K2-415b, and its similarities (and differences) to our own home world might shed some light on how Earth-like planets form and evolve in different ways, in systems very different from our own.

"Small planets around M dwarfs are a good laboratory to explore the atmospheric diversity of rocky planets and the conditions at which a habitable terrestrial planet can exist," writes an international team of astronomers led by Teruyuki Hirano of the Astrobiology Center in Japan.

"Being one of the lowest mass stars known to host an Earth-sized transiting planet, K2-415 will be an interesting target for further follow-up observations, including additional radial velocity monitoring and transit spectroscopy."

The research has been accepted for publication in The Astronomical Journal, and is available on preprint server arXiv.

The Milky Way galaxy is a big place, with lots of interesting worlds in it, but so far it has proven evasive on one of the biggest questions humanity has ever asked: why are we here? And not just why, but how, and why this planet, and is there anywhere else out there where life could potentially happen?

Since Earth is the only place in the Universe where we know for a fact life has emerged, one of the tools that could help deliver answers is a population of exoplanets that are similar to Earth. Similar in size, composition, temperature, mass; perhaps even planetary system architecture.

The best population of exoplanets to start this research is small, Earth-sized worlds orbiting small stars, relatively nearby, in such a way that they transit, or pass between us and the star. That's because they're the best candidates for characterizing an atmosphere.

As the exoplanet passes in front of the star, a fraction of the star's light will pass through an atmosphere, with some wavelengths on the spectrum being absorbed or amplified by elements in the atmosphere.

Around smaller, dimmer, cooler stars like red dwarfs, the habitable temperature zone is much closer to the star than it is around a star like the Sun. This means that the orbital period is shorter, so many transits can be recorded and stacked to amplify the spectrum data. And, obviously, closer stars will appear brighter, which will make such observations easier.

Small exoplanets, however, are harder to find than large ones. Within 100 light-years of the Solar System, just 14 exoplanets smaller than 1.25 times the radius of Earth have been found orbiting red dwarf stars – including all 7 worlds in the TRAPPIST-1 system.

This is an instance where there's no such thing as too many data points, and Hirano and his colleagues seem to have found a doozy. The exoplanet K2-415b is 1.015 times the radius of Earth, orbiting one of the smallest red dwarf stars found hosting an Earth-sized world. The star, K2-415, is just 16 percent of the mass of the Sun.

The exoplanet was first spotted in data from the now-retired Kepler planet-hunting telescope in 2017, and it also appeared in data from Kepler's successor, TESS.

The researchers followed up, taking infrared observations to see if they could detect a faint 'wobble' in the star's motion, as it is ever-so-slightly tugged about on the spot by the gravity of the exoplanet.

This wealth of data revealed the presence of a world, as well as its characteristics. The amount of starlight blocked when the exoplanet transits can be used to calculate the planetary radius. The amount of wobble gives its mass.

Those two parameters can be combined to calculate the exoplanet's density. And, of course, the periodicity of the transits reveals the exoplanet's orbital period.

This is where K2-415b starts to seriously differ from Earth. Although the exoplanet is about Earth-sized, its mass is much higher, around three times that of Earth. This means that K2-415b is denser than Earth, too.

And it's much, much closer to its star: It has an orbital period of just four days. It's true that the habitable zone of a red dwarf star can be much closer than the Sun's habitable zone, with orbits measurable in days rather than months, but that's a little too close for comfort, even for a red dwarf.

However, only a little. K2-415b sits just inside the rim of K2-415's habitable zone. That could mean that it still has an atmosphere to probe. In the Solar System, Venus is just inside the habitable zone, and its atmoIt's also possible that K2-415 is a multi-planet system; this raises the possibility of a currently undetected exoplanet in the star's habitable zone.

So we're unlikely to find signs of life on K2-415b. But the system represents an excellent target for exoplanet atmospheric characterization, and follow-up surveys looking for hidden, potentially life-harboring worlds.

The research has been accepted for publication in The Astronomical Journal, and is available on arXiv.sphere is a dense and intriguing horror show.

It's also possible that K2-415 is a multi-planet system; this raises the possibility of a currently undetected exoplanet in the star's habitable zone.

So we're unlikely to find signs of life on K2-415b. But the system represents an excellent target for exoplanet atmospheric characterization, and follow-up surveys looking for hidden, potentially life-harboring worlds.

The research has been accepted for publication in The Astronomical Journal, and is available on arXiv. - Science Alert 

Apr 29, 2023

Children’s Risk of Suicide

Unlike in adults, suicide risk among children is lowest during the summer and higher during the school year. Understanding these patterns can help prevent and treat suicidality

By Tyler Black

Pediatricians, child psychologists and psychiatrists, social workers and pediatric emergency teams know something that many people who care for children don’t: we are much busier during the school year. I’m a full-time emergency psychiatrist who works at a major children’s hospital, and often when children come in for a mental health crisis, one of the main stressors they discuss is school.

I’m sure most people assume I commonly prescribe medications as a physician, but one of my most common “prescriptions” is advocating for reducing school burden and load. In a 2013 American Psychological Association survey, 83 percent of adolescents stated that school was a cause or significant source of stress. In a 2017 survey of school leaders in the U.K., 82 percent reported increased mental health issues among primary school children during the time of national examinations. In studies in 2013 and 2015, scientists studying homework in the U.S. found that primary school children were averaging 30 minutes of such work per night, while high-performing secondary students were averaging more than three hours per night, at the cost of their physical health and schoolwork-life balance.

Whether we are talking about referrals to mental health programs for crisis, presentations to emergency departments for mental health issues, admissions to intensive care units for urgent treatment of suicide attempts or deaths by suicide, an association with school is clear. We are able to visualize this in a number of ways.

By using the Centers for Disease Control and Prevention’s Wonder database to find information on pediatric (17 years of age or younger) deaths by suicide, I have created a “heat map” of youth suicide, and a school-day association is plain to see. On weekdays and during school months, there is a significant elevation of suicide deaths in children.

Looking at the monthly data, we can see that this elevation is not trivial: during school months, the increase in pediatric suicides ranges between 30 and 43 percent. This is in sharp contrast with adults, where we see suicide rates typically peak in summer months.


This situation has not improved over time: Compared with summer weekends, school-month weekdays from 2016 to 2019 show a pediatric suicide rate increase of 62 percent. The increase was 42% from 1999 to 2015.

If we look at far more common events, such as emergency room visits for mental health conditions, we see a strikingly similar pattern. These data come from participating hospitals in a collection done by the CDC.


School comes with many things, good and bad. School can be wonderful, with learning experiences, social successes and a sense of connection to others. But it can also be incredibly stressful because of academic burden, bullying, health- and disability-related barriers, discrimination, lack of sleep and sometimes abuse. I often liken going to school to a child’s full-time job. The child has co-workers (classmates arranged by hierarchy), supervisors (teachers), bosses (administrators and principals) and overtime (homework). And they have very early work hours (most schools have hours that are very incompatible with children’s sleep patterns). Of course, work can be rewarding, but it’s also stressful.

Any time I present these data to teachers, parents, principals or school administrators, they are shocked. This should be common knowledge. Pediatric suicides and mental health crisis rates increase sharply when school is in and ease when school is out. This pattern is also found in other jurisdictions, such as Japan, Germany and Finland.

There are a number of ways to potentially mitigate this distress that I wish those responsible for our children’s education would explore. Some suggestions I’d put forth:

Reduce homework (preferably get rid of it). Some of the best educational science available shows that excessive homework is of limited benefit and in fact harms children’s health and well-being.

Add a mental health curriculum. We have developed incredible educational goals for math, reading, science and the arts. There should be a dedicated pathway for a much more universal and necessary learning: how to take care of yourself; how to look out for and help others; and how to improve both the detection and prevention of mental health crises.

Take bullying seriously and don’t just focus on the bullies. The bullied and bullies often come from similar backgrounds (histories of abuse, trauma, chaos, deprivation, parental detachment, though this certainly isn’t universally the case). But whereas the bullied tend to be internalizers, the bullies are more often externalizers. Bullies who were once victims of bullying have the highest risk of having psychiatric problems in the future.

Restore funding for playtime, music and art in school and de-emphasize academic overload. Children need relaxation, comfort, beauty, fun and play. Children who have opportunities to play and rest will learn more in their academics, and they will be able to sustain their development as they grow.

End “perfect attendance” awards and goals. While problematic truancy should be addressed, there is no less realistic notion for the rest of one’s life than the idea of “perfect attendance.” We should all, from time to time, recognize when we are at our limit and need a break. Children should be encouraged to report when they can do so and be supported.

Start school later. How many more decades of research do we need to show that children need more sleep and that adolescents do better in school when the day starts later? It’s time to make serious structural changes to the early-morning wake-up times.

Be nonjudgmental and respect children’s identity and identity formation. This is not a “woke” concept. This is a caring, compassionate concept that works for all children all the time.

Recognize and address child abuse within schools. There exist (and many readers may likely recall) teachers who are abusive, punitive and cruel. In one 2015 study, 44 percent of undergraduates recalled a time in K–12 school that they labeled as emotional abuse by a teacher. And in another study published in 2019, 3.4 percent of seventh- and eighth-grade students reported teachers bullied them.

Every year my colleagues in the emergency department brace for the coming mid-September wave, as every year our mental health crisis presentation volumes double and our days become much busier. Likely not coincidentally, in my jurisdiction, school starts in the second week of September.

In the new school year, if you are someone who works with school-age children, ask yourself what you could be doing to reduce pressure or improve quality of life for the children in your care. This would truly be suicide prevention.-Scientific America


Jan 28, 2023

Sticker Looks Inside The Body

 By Sophie Bushwick

Ultrasound scanners, which image the inside of the human body, are a life-saving medical tool. Now researchers have shrunk the handheld ultrasound probe—which typically requires a highly trained technician to move over the skin—down to a flat chip that is the size of a postage stamp and sticks to the skin with a special bioadhesive. The new device can record high-resolution videos for two days at a stretch, capturing blood vessels and hearts laboring during exercise or stomachs expanding and shrinking as test subjects gulp juice and then digest it.

“The beauty of this is, suddenly, you can adhere this ultrasound probe, this thin ultrasound speaker, to the body over 48 hours,” says Xuanhe Zhao, a mechanical engineer at the Massachusetts Institute of Technology and co-author of a paper describing the new device, which was published in Science on Thursday. By recording still pictures and videos of internal organs during this time, a wearable imaging device could be used to diagnose heart attacks and malignant tumors, test the effectiveness of medications and assess general heart, lung or muscle health. “This can potentially change the paradigm of medical imaging by empowering long-term continuous imaging,” Zhao adds, “and it can change the paradigm of the field of wearable devices.”

Traditional ultrasounds are great at peering beneath the skin without causing damage to the body, but access to such scans is limited. “The conventional handheld ultrasound requires well-trained technicians to put the probe properly on the skin and apply some liquid gel between the probe and skin,” says Nanshu Lu, a mechanical engineer at the University of Texas at Austin, who was not involved in the new research but co-wrote an accompanying analysis in Science. “And as you can imagine, it’s quite tedious and very short-term, very constrained.” Because they require an experienced human operator, Lu explains, these scans are expensive, and they cannot be used in tests where the subject is exercising or putting their body under stress from heat or extreme environments. “Conventional ultrasounds have a lot of limitations,” she says. “If we can make ultrasound sensors wearable and mobile and accessible, it will open a lot of new possibilities.”

Thanks to their potential versatility, other researchers have attempted to make stick-on ultrasound patches. But in order to adhere to soft, stretchy skin, earlier devices were designed to be stretchable themselves. This form factor weakened image quality because it could not accommodate as many transducers—units that, in this case, transform electrical power into sound waves with frequencies too high for human ears to detect. An ultrasound probe sends these waves through a layer of gooey gel into the human body, where they bounce off organs and other internal structures and then return to the transducer array. This converts the mechanical waves back to electrical signals and sends them to a computer for translation into images.

The more transducers, the better the image quality. “It’s very similar to a camera,” explains Philip Tan, an electrical engineer and a graduate student at Lu’s lab at U.T. Austin, who was also not involved with the new study but co-wrote the analysis piece. A stretchy stick-on ultrasound probe, which must be able to flex every time the skin moves, cannot pack as many transducers into the array—and when the wearer moves, the configuration of transducers shifts and makes it difficult to capture stable images.

Instead of making the device itself stretchy, Zhao and his team attached a rigid probe, just three millimeters thick, to a flexible layer of adhesive. This adhesive replaces the gooey liquid placed between a traditional ultrasound wand and the skin, and it is a hybrid of a water-rich polymer called a hydrogel and a rubberlike material called an elastomer. “It is a piece of solid hydrogel containing over 90 percent water, but it is in a solid state like Jell-O,” Zhao says. “We cover the surface of this Jell-O with this very thin membrane of elastomer so that the water inside the Jell-O will not evaporate out.” This bioadhesive not only stuck the probe firmly to the skin for 48 hours, but it also provided a cushioning layer that protected the rigid electronics from the flexing of skin and muscles.

To image different body systems, Zhao’s team tested versions of the probe that produce waves at different frequencies and thus penetrate the body to different depths. For instance, a high frequency such as 10 megahertz might make it to a couple of centimeters beneath the skin. The researchers used this frequency to capture the action of blood vessels and muscles as test subjects shifted from sitting to standing or exercised vigorously. A lower frequency of three megahertz goes deeper, more like six centimeters, to capture internal organs. Using this frequency, the researchers imaged the four chambers of a subject’s heart, and recorded the stomach of another emptying out as their system processed a couple of cups of juice. The researchers also compared the images gathered with their rigid ultrasound probe with those captured by a stretchable ultrasound device, Zhao says. “You can see the resolution of ours is almost one order of magnitude [10 times] higher than the stretchable ultrasound,” he adds.

An imaging device that maintains a continuous watch over specific parts of the body could be used to monitor and diagnose a variety of ailments. Doctors could keep a close eye on the growth of a tumor over time. Someone at high risk of hypertension might wear an ultrasound patch to measure their high blood pressure, alerting them when the pressure spikes or tracking whether a medication is helping. A COVID patient could stay home, knowing that an imaging device would alert them if their illness caused a lung infection severe enough to require hospitalization. Perhaps the most important application could be in the detection and diagnosis of heart attacks. “Cardiovascular disease is ... the leading cause of death in the whole world, also in the U.S.,” Zhao says. Heart health is on the radar of other wearable device developers. For instance, smart watches such as the Apple Watch are capable of tracking the electrical signals that indicate heart activity with a so-called electrocardiogram (ECG or EKG). This can be used to diagnose heart attacks—at least in some cases. “There are already studies showing that EKG can only diagnose around 20 percent of heart attacks. The majority of heart attacks actually require imaging modalities, such as ultrasound imaging, to diagnose,” Zhao says. Continuous imaging of a patient’s heart could capture their symptoms and provide an early diagnosis.

“The big selling point of this new device is that it opens new types of medical diagnosis that can’t be done in a static setting,” Tan says. To assess heart health, for instance, it’s helpful to measure the organ’s activity while exercising—but it’s hard to hold an ultrasound wand against a running subject’s goo-covered chest. “With a wearable ultrasound patch, where you wouldn’t have to hold the transducer on the person, they were actually able to show that you’re able to get very high-quality images of the heart even during motion,” Tan adds.

The bioadhesive device is not ready for action yet, however. For one thing, it still has to be physically plugged into a computer that can collect and analyze the data the probe produces. “We connect this probe through a wire to a data acquisition system,” Zhao says. “But my group is working very hard to miniaturize and integrate everything into our wireless device.” He ultimately plans to upgrade the patch with a miniaturized power source and a wireless data-transmission system. This is a feasible goal, Lu and Tan agree, thanks to shrinking electronic components and fabrication methods that allow these features to be combined into an “ultrasound on a chip.” Lu suggests that if the field can attract federal and private investments, such a device could be feasible within five years, although it would still have to earn approval from federal regulators.

Ultimately, ultrasound stickers could join the ranks of wearables that monitor human health, including existing devices that gather information about heart rate, sleep quality and even stress. “Our human body is radiating a lot of a highly personal, highly continuous, distributed and multimodal data about our health, our emotion, our attention, our readiness, and so on. So we’re full of data,” Lu says. “The question is how to get them reliably and continuously.” -Scientific America


Sep 24, 2022

Sticker Looks Inside The Body

A new stick-on ultrasound patch can record the activity of hearts, lungs and other organs for 48 hours at a time

By Sophie Bushwick

Ultrasound scanners, which image the inside of the human body, are a life-saving medical tool. Now researchers have shrunk the handheld ultrasound probe—which typically requires a highly trained technician to move over the skin—down to a flat chip that is the size of a postage stamp and sticks to the skin with a special bioadhesive. The new device can record high-resolution videos for two days at a stretch, capturing blood vessels and hearts laboring during exercise or stomachs expanding and shrinking as test subjects gulp juice and then digest it.

“The beauty of this is, suddenly, you can adhere this ultrasound probe, this thin ultrasound speaker, to the body over 48 hours,” says Xuanhe Zhao, a mechanical engineer at the Massachusetts Institute of Technology and co-author of a paper describing the new device, which was published in Science on Thursday. By recording still pictures and videos of internal organs during this time, a wearable imaging device could be used to diagnose heart attacks and malignant tumors, test the effectiveness of medications and assess general heart, lung or muscle health. “This can potentially change the paradigm of medical imaging by empowering long-term continuous imaging,” Zhao adds, “and it can change the paradigm of the field of wearable devices.”

.Traditional ultrasounds are great at peering beneath the skin without causing damage to the body, but access to such scans is limited. “The conventional handheld ultrasound requires well-trained technicians to put the probe properly on the skin and apply some liquid gel between the probe and skin,” says Nanshu Lu, a mechanical engineer at the University of Texas at Austin, who was not involved in the new research but co-wrote an accompanying analysis in Science. “And as you can imagine, it’s quite tedious and very short-term, very constrained.” Because they require an experienced human operator, Lu explains, these scans are expensive, and they cannot be used in tests where the subject is exercising or putting their body under stress from heat or extreme environments. “Conventional ultrasounds have a lot of limitations,” she says. “If we can make ultrasound sensors wearable and mobile and accessible, it will open a lot of new possibilities.”0

Thanks to their potential versatility, other researchers have attempted to make stick-on ultrasound patches. But in order to adhere to soft, stretchy skin, earlier devices were designed to be stretchable themselves. This form factor weakened image quality because it could not accommodate as many transducers—units that, in this case, transform electrical power into sound waves with frequencies too high for human ears to detect. An ultrasound probe sends these waves through a layer of gooey gel into the human body, where they bounce off organs and other internal structures and then return to the transducer array. This converts the mechanical waves back to electrical signals and sends them to a computer for translation into images.

The more transducers, the better the image quality. “It’s very similar to a camera,” explains Philip Tan, an electrical engineer and a graduate student at Lu’s lab at U.T. Austin, who was also not involved with the new study but co-wrote the analysis piece. A stretchy stick-on ultrasound probe, which must be able to flex every time the skin moves, cannot pack as many transducers into the array—and when the wearer moves, the configuration of transducers shifts and makes it difficult to capture stable images.

Instead of making the device itself stretchy, Zhao and his team attached a rigid probe, just three millimeters thick, to a flexible layer of adhesive. This adhesive replaces the gooey liquid placed between a traditional ultrasound wand and the skin, and it is a hybrid of a water-rich polymer called a hydrogel and a rubberlike material called an elastomer. “It is a piece of solid hydrogel containing over 90 percent water, but it is in a solid state like Jell-O,” Zhao says. “We cover the surface of this Jell-O with this very thin membrane of elastomer so that the water inside the Jell-O will not evaporate out.” This bioadhesive not only stuck the probe firmly to the skin for 48 hours, but it also provided a cushioning layer that protected the rigid electronics from the flexing of skin and muscles.

To image different body systems, Zhao’s team tested versions of the probe that produce waves at different frequencies and thus penetrate the body to different depths. For instance, a high frequency such as 10 megahertz might make it to a couple of centimeters beneath the skin. The researchers used this frequency to capture the action of blood vessels and muscles as test subjects shifted from sitting to standing or exercised vigorously. A lower frequency of three megahertz goes deeper, more like six centimeters, to capture internal organs. Using this frequency, the researchers imaged the four chambers of a subject’s heart, and recorded the stomach of another emptying out as their system processed a couple of cups of juice. The researchers also compared the images gathered with their rigid ultrasound probe with those captured by a stretchable ultrasound device, Zhao says. “You can see the resolution of ours is almost one order of magnitude [10 times] higher than the stretchable ultrasound,” he adds.

An imaging device that maintains a continuous watch over specific parts of the body could be used to monitor and diagnose a variety of ailments. Doctors could keep a close eye on the growth of a tumor over time. Someone at high risk of hypertension might wear an ultrasound patch to measure their high blood pressure, alerting them when the pressure spikes or tracking whether a medication is helping. A COVID patient could stay home, knowing that an imaging device would alert them if their illness caused a lung infection severe enough to require hospitalization. 

Perhaps the most important application could be in the detection and diagnosis of heart attacks. “Cardiovascular disease is ... the leading cause of death in the whole world, also in the U.S.,” Zhao says. Heart health is on the radar of other wearable device developers. For instance, smart watches such as the Apple Watch are capable of tracking the electrical signals that indicate heart activity with a so-called electrocardiogram (ECG or EKG). This can be used to diagnose heart attacks—at least in some cases. “There are already studies showing that EKG can only diagnose around 20 percent of heart attacks. The majority of heart attacks actually require imaging modalities, such as ultrasound imaging, to diagnose,” Zhao says. Continuous imaging of a patient’s heart could capture their symptoms and provide an early diagnosis.

“The big selling point of this new device is that it opens new types of medical diagnosis that can’t be done in a static setting,” Tan says. To assess heart health, for instance, it’s helpful to measure the organ’s activity while exercising—but it’s hard to hold an ultrasound wand against a running subject’s goo-covered chest. “With a wearable ultrasound patch, where you wouldn’t have to hold the transducer on the person, they were actually able to show that you’re able to get very high-quality images of the heart even during motion,” Tan adds.

The bioadhesive device is not ready for action yet, however. For one thing, it still has to be physically plugged into a computer that can collect and analyze the data the probe produces. “We connect this probe through a wire to a data acquisition system,” Zhao says. “But my group is working very hard to miniaturize and integrate everything into our wireless device.” He ultimately plans to upgrade the patch with a miniaturized power source and a wireless data-transmission system. This is a feasible goal, Lu and Tan agree, thanks to shrinking electronic components and fabrication methods that allow these features to be combined into an “ultrasound on a chip.” Lu suggests that if the field can attract federal and private investments, such a device could be feasible within five years, although it would still have to earn approval from federal regulators.

Ultimately, ultrasound stickers could join the ranks of wearables that monitor human health, including existing devices that gather information about heart rate, sleep quality and even stress. “Our human body is radiating a lot of a highly personal, highly continuous, distributed and multimodal data about our health, our emotion, our attention, our readiness, and so on. So we’re full of data,” Lu says. “The question is how to get them reliably and continuously.” -Scientific America

Feb 12, 2022

GoFundMe Bans Anti-Vaxxers


By Julia Arciga

Anti-vaxxers have long used GoFundMe to raise money to spread their dangerous message—but now the site is cutting them off, The Daily Beast has learned.

“Campaigns raising money to promote misinformation about vaccines violate GoFundMe’s terms of service and will be removed from the platform,” spokesman Bobby Whithorne told The Daily Beast.

“We are conducting a thorough review and will remove any campaigns currently on the platform.”

It’s the latest crackdown on fact-challenged activists who believe the medical establishment, the government, and the pharmaceutical industry are engaged in a conspiracy to hurt American children.

The U.S. anti-vax movement has been blamed for two outbreaks of measles that have infected some 300 people—mostly children—in New York and the Pacific Northwest.

Last week, the American Medical Association warned social-media giants, including Amazon, Facebook, Google, Pinterest, Twitter, and YouTube, that they were helping to amplify the propaganda and confuse parents.

But as The Daily Beast has previously reported, anti-vaxxers have also used sites like GoFundMe to underwrite their messaging campaigns.

Whithorne said such fundraisers were “extremely rare” and that the site had removed fewer than 10 campaigns so far.

The Daily Beast found fundraisers benefiting or promoted by anti-vaccination or “vaccine choice” groups brought in at least $170,000 in the last four years. They include:
  • Prominent anti-vax activist Larry Cook, who spent more money than anyone else boosting his message on Facebook and collected $79,900 on various GoFundMe campaigns.
  • A vaccine-exemption attorney’s legal defense fund, which raised $25,220, that was promoted by Health Freedom Idaho and Sarasota for Vaccine Choice.
  • Three campaigns promoted by A Voice for Choice’s Facebook page that raised $39,801.
Melissa Sullivan, executive vice president at Health Choice Connecticut, which raised $2,650 under its previous name, Vaccine Choice CT, said GoFundMe’s eviction was a “violation of the First Amendment” and suggested, without any supporting evidence, that the platform was “feeling pressure from Big Pharma.”

“Whether you believe it’s true or not, everyone is entitled to their opinion,” Sullivan said. “I would hope they would reconsider. This movement needs to be able to get funds in order to fight pharma giants like Merck and other vaccine manufacturers.”

The fundraising campaigns of Cook, who funded Facebook ads targeting women of child-bearing age in Washington state during the latest measles outbreak, appear to have been taken down earlier this week.

Cook, whose website contained a disclaimer that some donations might go to pay his “personal bills,” did not respond to The Daily Beast’s request for comment.

GoFundMe’s terms of service explicitly ban donations toward “products that make health claims that have not been approved or verified by the applicable local… or national regulatory body.”

Earlier this week, it banned campaigns that raise money to cover treatment by a controversial German cancer clinic that offers unproven “high-dose vitamin infusions” and “ozone therapy” treatments. GoFundMe told the Financial Times it would be “speaking to organizations and experts” in the U.S. and the U.K. to fight medical misinformation.

“We know we have a major role to play in big issues like this, and as we continue to grow... our policies will continue to evolve to make sure we are best serving people,” a spokesman told the newspaper.

Tara Smith, professor of epidemiology at Kent State University, praised GoFundMe’s ban, but said she suspects the anti-vax movement will find other ways to raise money and spread its message.

“I appreciate the initiative, but [this movement] fundraised before GoFundMe and I’m sure they will find other ways after their campaigns are removed,” she said. “I suspect they will just go back to sending mailers or back to newsletters online to solicit donations in other ways.”

Smith said she was not surprised by the amount of money donated to anti-vaxxer groups through the site.

“There are a lot of true believers, and I know they’re willing to support that with their money,” she said “I just think of all the science that money could fund, and it makes me sad.”

In recent days, Facebook and YouTube announced efforts to reduce anti-vax content, and Amazon has started removing some books and documentaries. Now that GoFundMe has joined them, activists have started to look for new sources.

Sullivan, of Health Choice Connecticut, said her organization started a MeWe page in case Facebook boots it. In a post to more than 160,000 members in his private anti-vax Facebook group last week, Cook pitched a new idea that he claimed could “topple the vaccine industry”—an anti-vax media outlet.

“What if I created a website where parents—like you—could submit stories online that could be reviewed and easily published?... Like a natural parenting blog, only, with dozens or even hundreds of authors?” he wrote. “If done right, I think this could be a rapid deployment of stories to grab more attention… Get your stories ready NOW so that when we launch we can launch big.” -Daily Beast

May 19, 2019

Female Dragonflies Fake Death

By Hannah Osborne

In order to avoid males of the species bothering them for sex, female dragonflies fake their own deaths, falling from the sky and lying motionless on the ground until the suitor goes away.

A study by Rassim Khelifa, a zoologist from the University of Zurich is the first time scientists have seen odonates feign death as a tactic to avoid mating, and a rare instance of animals faking their own deaths for this purpose. Odonates is the order of carnivorous insects that includes dragonflies and damselflies.

Khelifa had been collecting the eggs of odonates in the Swiss Alps for experiments into how temperature affects larvae. But over the two summers he spent there, he noticed unusual behavior among female dragonflies of the species Aeshna juncea .

In a study published in the journal Ecology, he wrote that on July 5, 2015 “while I was waiting at a pond near Arosa, at about 2,000 meter elevation, I witnessed a dragonfly dive to the ground while being pursued by another dragonfly... the individual that crashed was a female, and that she was lying motionless and upside down on the ground.

“Upside down is an atypical posture for a dragonfly. The male hovered above the female for a couple seconds and then left. I expected that the female could be unconscious or even dead after her crash landing, but she surprised me by flying away quickly as I approached. The question arose: Did she just trick that male? Did she fake death to avoid male harassment? If so, this would be the first record of sexual death feigning in odonates.”

Khelifa notes there are few instances of animals faking their own deaths, with four others known to science. These include two species of robber fly, the European mantis and the spider species Pisaura mirabilis, where the males fake death in order to avoid being killed after mating. One study describes the females of another species of dragonfly lying motionless—but researchers did not suggest it was faking death.

Over the next few months, Khelifa documented dozens of cases where females would crash land and play dead while being pursued by a male. He also looked at the reproductive behavior of A. juncea to try to work out why females would do this.

His observations showed females would arrive at the ponds where the males were waiting to mate. Males would intercept females mid-air before copulating somewhere nearby. The male then flew away and the female laid eggs on her own, without any protection—unlike many other dragonfly species, where the male will guard the female.

“Females became vulnerable to male coercion at that time because conspecific males were constantly patrolling each corner of the pond looking for a mate,” Khelifa writes.

Further observations showed that the more male competition there was, the more likely female dragonflies were to fake their own deaths. In 86 percent of cases, females would crash to the ground. Those that kept flying “were all intercepted by a male.” “Of the 27 motionless females, 21 (77.7 percent) were successful in deceiving the coercive male,” he adds.

Khelifa suggested this behavior is common among the female of this dragonfly species, and that it could have evolved for a number of reasons: “On one hand, this behavior could have resulted from exaptation. Since death feigning already exists in the behavioral repertoire of dragonflies, females of the moorland hawker expanded the use of this anti-predatory function to avoid male coercion,” he wrote. “On the other hand, the origin of this exaptation is probably sexual conflict where each sex adopts reproductive strategies that best serve its own survival and reproductive success.”

Even though it is a risky strategy, faking death appears to help females survive longer and produce more offspring by avoiding coercion. “Sexual death feigning is one of the rarest behaviors in nature, and due to its scarcity, it has received little attention in behavioral ecology,” the study said. “Currently, it is restricted only to arthropods. It would be interesting to know whether this scarcity is true or just an artifact related to the lack of behavioral investigations or difficulty in detecting this behavior.”  -News Week

Apr 28, 2019

London Patient Is Second To Obtain Long-Term HIV Remission

An HIV-positive man in London has become the second known person in the world to have long-term HIV remission for over a year after receiving a bone marrow transplant from a donor with an HIV-resistant genetic mutation.

After three years of bone marrow stem cell treatment, tests are now showing no trace of HIV in the patient, according to Reuters.

“There is no virus there that we can measure,” Ravindra Gupta, a professor and HIV biologist who co-led the team treating the man, told the outlet. “We can’t detect anything.”

This milestone in HIV treatment is being heralded as proof that scientists can one day eradicate the virus completely, but it does not mean a cure has been found. The patient is described by doctors as “functionally cured” and “in remission," and confirm it’s too early to say he's fully cured.

He is now the second person in the world to be in remission over a year, after getting taken off meds.

The first patient was Timothy Ray Brown, i.e. "the Berlin patient," who in 2007 underwent a similar treatment and is currently HIV-free. The man lives in the United States.

Over 37 million people worldwide are currently HIV-positive and the AIDS epidemic has killed more than 35 million people since its original outbreak in the 1980s. Research has been ongoing for decades with few breakthroughs for an eradicated cure documented.

This new patient in London was originally diagnosed in 2003 and is asking for his medical team to not release any identifying information as it continues to research this case. Researchers are now hopeful that this breakthrough could help them in figuring out how to potentially end HIV globally. –HIV Plus Mag

HIV Vaccine: How Close Are We?

Introduction

Some of the most important medical breakthroughs of the past century involved the development of vaccines to protect against viruses such as:
  • smallpox
  • polio
  • hepatitis A and hepatitis B
  • human papillomavirus (HPV)
  • chickenpox

But one virus still thwarts those who want to create a vaccine to guard against it: HIV.

HIV was first identified in 1984. The U.S. Department of Health and Human Services announced at the time that they hoped to have a vaccine ready within two years.

Despite many trials of possible vaccines, though, a truly effective vaccine is still not available. Why is it so difficult to conquer this disease? And where are we in the process?

Obstacles to an HIV vaccine

It’s so hard to develop a vaccine for HIV because it’s different from other types of viruses. HIV doesn’t fit typical vaccine approaches in several ways:

1. The immune systems of almost all people are ‘blind’ to HIV

The immune system, which fights disease, doesn’t respond to the HIV virus. It produces HIV antibodies, but they only slow the disease. They don’t stop it.

2. Vaccines are typically made to mimic the immune reaction of recovered people

However, almost no people have recovered after contracting HIV. As a result, there’s no immune reaction that vaccines can mimic.

3. Vaccines protect against disease, not infection

HIV is an infection until it progresses to stage 3, or AIDS. With most infections, vaccines buy the body more time to clear the infection on its own before disease occurs.

However, HIV has a long dormant period before it progresses to AIDS. During this period, the virus hides itself in the DNA of the person with the virus. The body can’t find and destroy all of the hidden copies of the virus to cure itself. So, a vaccine to buy more time won’t work with HIV.

4. Killed or weakened HIV viruses can’t be used in a vaccine

Most vaccines are made with killed or weakened viruses. Killed HIV doesn’t work well to produce an immune response in the body, though. Any live form of the virus is too dangerous to use.

5. Vaccines are typically effective against diseases that are rarely encountered

These include diphtheria and hepatitis B. But people with known risk factors for HIV might be exposed to HIV daily. This means there’s more chance for infection that a vaccine can’t prevent.

6. Most vaccines protect against viruses that enter the body through the respiratory or gastrointestinal systems

More viruses enter the body in these two ways, so we have more experience addressing them. But HIV enters the body most often through genital surfaces or the blood. We have less experience protecting against viruses that enter the body in those ways.

7. Most vaccines are tested thoroughly on animal models

This helps ensure that they’re likely to be safe and effective before they’re tried on humans. However, no good animal model for HIV is available. Any testing that’s been done on animals hasn’t shown how humans would react to the tested vaccine.

8. The HIV virus mutates quickly

A vaccine targets a virus in a particular form. If the virus changes, the vaccine may not work on it anymore. HIV mutates quickly, so it’s hard to create a vaccine to work against it.

Prophylactic vs. therapeutic vaccines
Despite these obstacles, researchers continue to try to find a vaccine. There are two main types of vaccines: prophylactic and therapeutic. Researchers are pursuing both for HIV.

Most vaccines are prophylactic, which means they prevent a person from getting a disease. Therapeutic vaccines, on the other hand, are used to increase the body’s immune response to fight disease that the person already has. Therapeutic vaccines are also considered treatments.

Therapeutic vaccines are being investigated for several conditions, such as:
  • cancerous tumors
  • hepatitis B
  • tuberculosis
  • Malaria
  • the bacteria that cause gastric ulcers
An HIV vaccine would theoretically have two goals. First, it could be given to people who don’t have HIV to prevent contracting the virus. This would make it a prophylactic vaccine.

But HIV is also a good candidate for a therapeutic vaccine. Researchers hope a therapeutic HIV vaccine could reduce a person’s viral load.

Types of experimental vaccines

Researchers are trying many different approaches to develop an HIV vaccine. Possible vaccines are being explored for both prophylactic and therapeutic uses.

Currently, researchers are working with the following types of vaccines:
  • Peptide vaccines use small proteins from HIV to trigger an immune response.
  • Recombinant subunit protein vaccines use larger pieces of proteins from HIV.
  • Live vector vaccines use non-HIV viruses to carry HIV genes into the body to trigger an immune response. The smallpox vaccine uses this method.
  • Vaccine combinations, or “prime-boost” combinations, use two vaccines one after another to create a stronger immune response.
  • Virus-like particle vaccines use a noninfectious HIV lookalike that has some, but not all, HIV proteins.
  • DNA-based vaccines use DNA from HIV to trigger an immune response.
Clinical trial stumble

An HIV vaccine study, known as the HVTN 505 study, ended in October of 2017. It studied a prophylactic approach that used a live vector vaccine.

A weakened cold virus called Ad5 was used to trigger the immune system to recognize (and thus be able to fight) HIV proteins. More than 2,500 people were recruited to be part of the study.

The study was stopped when researchers found that the vaccine didn’t prevent HIV transmission or reduce the viral load. In fact, 41 people on the vaccine contracted HIV, while only 30 people on a placebo contracted it.

There’s no proof that the vaccine made people more likely to contract HIV. However, with the previous failure in 2007 of Ad5 in a study called STEP, researchers grew concerned that anything that caused immune cells to attack HIV might increase the risk of contracting the virus.

Other current trials

A current vaccine trial that started in 2015 involves the International AIDS Vaccine Initiative (IAVI). This trial of a prophylactic vaccine studies people in:
  • United States
  • Rwanda
  • Uganda
  • Thailand
  • South Africa
The trial adopts a live vector vaccine strategy, using the Sendai virus to carry HIV genes. It also uses a combination strategy, with a second vaccine to boost the body’s immune response. Data collection from this study is complete. Results are expected in 2022.

Another important approach currently being studied is the use of vectored immunoprophylaxis.

With this approach, a non-HIV virus is sent into the body to enter cells and produce what’s called broadly neutralizing antibodies. This means the immune response would target all HIV strains. Most other vaccines only target one strain.

The IAVI is currently running a study like this called IAVI A003 in the United Kingdom. The study ended in 2018, and results are expected soon.

The future of HIV vaccines

According to a 2018 report, $845 million was spent on HIV vaccine research in 2017. And to date, more than 40 potential vaccines have been tested.

There’s been slow progress toward a workable vaccine. But with each failure, more is learned that can be used in new attempts.

For answers to questions about an HIV vaccine or information on taking part in a clinical trial, a healthcare provider is the best place to start. They can answer questions and provide details about any clinical trials that might be a good fit. –Health Line

Mar 17, 2019

How Big Is Earth?

By Tim Sharp

Earth, the third planet from the sun, is the fifth largest planet in the solar system; only the gas giants Jupiter, Saturn, Uranus and Neptune are bigger. Earth is the largest of the terrestrial planets of the inner solar system, bigger than Mercury, Venus and Mars.

Radius, diameter and circumference

The radius of Earth at the equator is 3,963 miles (6,378 kilometers), according to NASA's Goddard Space Flight Center. However, Earth is not quite a sphere. The planet's rotation causes it to bulge at the equator. Earth's polar radius is 3,950 miles (6,356 km) — a difference of 13 miles (22 km).

Using those measurements, the equatorial circumference of Earth is about 24,901 miles (40,075 km). However, from pole-to-pole — the meridional circumference — Earth is only 24,860 miles (40,008 km) around. This shape, caused by the flattening at the poles, is called an oblate spheroid.

Density, mass and volume

Earth's density is 5.513 grams per cubic centimeter, according to NASA. Earth is the densest planet in the solar system because of its metallic core and rocky mantle. Jupiter, which is 318 more massive than Earth, is less dense because it is made of gases, such as hydrogen.

Earth's mass is 6.6 sextillion tons (5.9722 x 1024 kilograms). It volume is about 260 billion cubic miles (1 trillion cubic kilometers).

The total surface area of Earth is about 197 million square miles (510 million square km). About 71 percent is covered by water and 29 percent by land.

Highest and lowest points

Mount Everest is the highest place on Earth above sea level, at 29,028 feet (8,848 meters), but it is not the highest point on Earth — that is, the place most distant from the center of the Earth. That distinction belongs to Mount Chimaborazo in the Andes Mountains in Ecuador, according to the National Oceanic and Atmospheric Administration (NOAA). Although Chimaborazo is about 10,000 feet shorter (relative to sea level) than Everest, this mountain is about 6,800 feet (2,073 m) farther into space because of the equatorial bulge.

The lowest point on Earth is Challenger Deep in the Mariana Trench in the western Pacific Ocean, according to the NOAA. It reaches down about 36,200 feet (11,034 meters) below sea level. –Space

Mar 3, 2019

Marijuana Compound Removes Toxic Alzheimer's Protein From The Brain

By Bec Crew

An active compound in marijuana called tetrahydrocannabinol (THC) has been found to promote the removal of toxic clumps of amyloid beta protein in the brain, which are thought to kickstart the progression of Alzheimer's disease.

The finding supports the results of previous studies that found evidence of the protective effects of cannabinoids, including THC, on patients with neurodegenerative disease.

"Although other studies have offered evidence that cannabinoids might be neuroprotective against the symptoms of Alzheimer's, we believe our study is the first to demonstrate that cannabinoids affect both inflammation and amyloid beta accumulation in nerve cells," says one of the team, David Schubert from the Salk Institute for Biological Studies in California. 

Schubert and his colleagues tested the effects of THC on human neurons grown in the lab that mimic the effects of Alzheimer's disease.

If you're not familiar with this special little compound, it's not only responsible for the majority of marijuana's psychological effects - including the high - thanks to its natural pain-relieving properties, it's also been touted as an effective treatment for the symptoms of everything from HIV and chemotherapy to chronic pain, post traumatic stress disorder, and stroke.

In fact, THC appears to be such an amazing medical agent, researchers are working on breeding genetically modified yeast that can produce it way more efficiently than it would be to make synthetic versions.

The compound works by passing from the lungs to the bloodstream, where it attaches to two types of receptors, cannabinoid receptor (CB) 1 and 2, which are found on cell surfaces all over the body.

In the brain, these receptors are most concentrated in neurons associated with pleasure, memory, thinking, coordination and time perception, and usually bind with a class of lipid molecules called endocannabinoids that are produced by the body during physical activity to promote cell-to-cell signalling in the brain. 

But THC can also bind to them in much the same way, and when they do, they start messing with your brain's ability to communicate with itself.

They can be a good and a bad thing, because while you might forget something important or suddenly be incapable of swinging a baseball bat, you'll probably feel amazing, and want to eat all the snacks:


Over the years, research has suggested that by binding to these receptors, THC could be having another effect on ageing brains, because it appears to helps the body clear out the toxic accumulations - or 'plaques' - of amyloid beta.

No one's entirely sure what causes Alzheimer's disease, but it's thought to result from a build-up of two types of lesions: amyloid plaques and neurofibrillary tangles. 

Amyloid plaques sit between the neurons as dense clusters of beta-amyloid molecules - a sticky type of protein that easily clumps together - and neurofibrillary tangles are caused by defective tau proteins that clump up into a thick, insoluble mass in the neurons. 

It's not clear why these lesions begin to appear in the brain, but studies have linked inflammation in the brain tissue to the proliferation of plaques and neurofibrillary tangles. So if we can find something that eases brain inflammation while at the same time encourages the body to clear out these lesions, we could be on the way to finding the first effective treatment for Alzheimer's ever.

Back in 2006, researchers at the Scripps Research Institute found that THC inhibits the formation of amyloid plaques by blocking the enzyme in the brain that produces them, and now Schubert and his team have demonstrated that it can also eliminate a dangerous inflammatory response from the nerve cells, ensuring their survival.

"Inflammation within the brain is a major component of the damage associated with Alzheimer's disease, but it has always been assumed that this response was coming from immune-like cells in the brain, not the nerve cells themselves," says one of the team, Antonio Currais. 

"When we were able to identify the molecular basis of the inflammatory response to amyloid beta, it became clear that THC-like compounds that the nerve cells make themselves may be involved in protecting the cells from dying."

It's exciting stuff, but it's so far only been demonstrated in neurons in the lab, so the next step will be for Schubert and his team to observe the link between THC and reduced inflammation and plaque build-up in a clinical trial.

They've reportedly already found a drug candidate called J147 that appears to have the same effects as THC, so this might be the way they can test the effects of THC without the government getting in the way.

Though it's worth adding that more recent legal changes since the time of this research around marijuana use in the USA may be making further research in this area a lot easier. –Science Alert

Feb 3, 2019

Discovery Of 150-year-old Iron Coffin Sheds Light On Forgotten Part Of History

by Leslie Gonzalez

Construction workers were working hard into the night when they heard their equipment hit something hard and loud. When inspecting the noise closer, they thought they had found something straight out of a horror movie: The mummified remains of a woman’s body. Still dressed in a nightgown and thick stockings, construction workers assumed it was the scene of a gruesome crime. But that wasn’t quite the case. Based on the PBS documentary, “The Woman in the Iron Coffin,” forensic archaeologists uncovered the truth behind the woman unearthed in Queens, New York, who she was, and how she got there.

There’s something under here

The whine of heavy machinery punctured the backdrop in Queens, New York. Men in hard hats dig deep and work hard near a railroad. As they sink their industrial shovels into the ground, a startling crunch of metal beneath the layer of earth catches their ears. Men signal the machinery to a halt.

At first, they thought they had hit a pipe. Workers approached the area to investigate. They sift away bits of dirt and realized they found something that didn’t belong. There were chunks of metal scattered around the trench, but that wasn’t the only thing they found. When they realized what they had on their hands, it sent chills up their spines.

2. It looked like a homicide

Under the layer of cold, autumn soil, what they initially thought was a pipe turned out to be large chunks of metal. As they mentally assembled the metal chunks together in their minds, they grew weary. Under some shrapnel of metal, they could see the outlines and fragments of a body.

It looked like it was still undergoing decomposition and decay. Though tattered and torn, there were clothes still wrapped around the body. The construction workers at the scene all stepped away from the discovery, afraid of disturbing what they believed was a crime scene. They alerted authorities and soon, New York’s homicide unit was on the scene.

3. The found metal around the human remains

When police officers arrived at the scene, they followed standard protocol for investigating a homicide. Among them were detectives Warren and Saenz, the two first responders. Because of the timing of the discovery, by the time they got there, it was dark. Street lights burned a copper-colored glow near the main street.

The detectives could barely see with their flashlights, but when they looked at the site in question, they were stumped. They looked at each other with confusion etched on their faces. When they recovered the body, they realized two things: one, the body was female and very well preserved, and two, she was surrounded by remnants of what looked like an iron coffin.

4. She was older than she appeared

Well preserved might actually be an understatement. In fact, the body was mummified, so much so that her burial clothes were in near perfect condition. She was wearing a white nightgown had a black horn comb tucked in her hair that set a light muslin veil behind her. Her hair was long and braided. Even the pigmentation of her skin was visible.

They woman they had found was African American and buried in an iron coffin. When detective concluded that that they might be dealing with something outside of their purview, they sought out the help of experts. They called in a forensic archaeologist.

5. He took one look at the metal and instantly knew what it was

With a proclivity for the old and strange, forensic archaeologist Scott Warnasch took an interest in the mummified remains found in Queens. That day, he never anticipated that he would get a call from New York’s homicide department. Warnasch rounded up a team and headed out to the area.

When they arrived, they were surrounded by police officers and yellow caution tape. They approached the body, Warnasch slowly worked around the remains. When he saw the metal fragments surrounding the woman, he didn’t have to pick up the pieces to know what he was dealing with. If it were anyone other than Warnasch, it would have taken longer to determine the significance of the metal pieces.

6. The iron was over 150 years old

Indeed, it was the fragments of metal that clued Warnasch into the fact that this death had occurred a while ago — a century ago. The woman they had unearthed was more than 150 years old. The homicide investigation was closed, but a historical inquiry opened up. Archaeologists had a field day (get it?) and soon, it was no longer in the hands of the law, but of historians and archaeologists.

Typically, forensic protocol calls for keeping most of the sensitive parts of the body covered until the last minute. That way, sun exposure and other weather-related factors don’t accelerate decomposition. However, something alarming was visible to the naked eye while excavating the remains.

7. They discovered something dangerous

Pushing away the loose dirt, the forensic team found lesions all over her body. They weren’t open wounds, but rather, a pattern that dotted her skull, her chest, all the way to her feet. It looked like smallpox. The investigation again took a turn, as they were now dealing with a highly contagious disease.

Because the body was so well preserved, that the smallpox was clearly visible on her skin. There were three things that needed to be done right away: taking extra safety precautions, and inform the morgue what they’d be dealing with, and call the Center for Disease Control (CDC).

8. They took samples of the body to see if the disease was viable

Medical researchers of the Center for Disease Control and Prevention arrived on the scene to collect samples of the woman’s infected skin. At first, researchers didn’t see the urgency of the situation. Believing the remains were in a deeper state of composition, they figured the disease was most likely dead by now.

But when they actually saw the body, they quickly realized the situation was more serious than they initially thought. They handled the body with extreme caution, especially because the symptoms of the disease were visible. Despite the danger, the team knew what to do. They took skin samples of the mummified remains, and sent it to the lab for testing.

9. Smallpox the epidemic

A contagion risk, smallpox was once one of the most dangerous diseases in the world. Smallpox is believed to have killed more people in human history than any other virus. It could go airborne and be transmitted through sneezing and coughing. Its transmission rate was roughly 60%, which was higher than Ebola during the 19th century.

In dense populations, the disease wrecked havoc. Nineteenth-century New York was an optimal breeding ground for the contagion. Due to poor sanitation systems and densely packed living quarters, those who lived in poverty were at an especially high risk. Our mystery mummy was one of those unfortunate souls who had contracted the disease.

10. The results were negative

The room held its breath as CDC analysts checked the results. A collective exhale when the results returned: The disease was not viable. Researchers and forensic analysts could continue their research with the remains safely. Though Warnasch’s job was over, he was still curious about the woman buried in the iron coffin.

Who was she, and why was she buried in a coffin made of iron? He wanted to know much more than how she died. His curiosity about the woman in the iron coffin tugged at him. He wanted to figure out the identity of this woman and learn her story. Warnasch turned to science.

11. They consulted the “Mummy Man”

There are a handful of people in the world who could comfortably categorize themselves as “mummy men.” One of the people who can say they are is retired professor Jerry Conlogue. Conlogue specializes in x-raying mummies. His research is able to ascertain history through the bones of the deceased. Once he obtains the necessary information, Conlogue can also make educated assumptions about how the deceased lived.

In doing so, Conlogue makes it possible to glimpse into the past. Conlogue’s not-so-secret weapon in his craft are computers. Specifically, 3-D imaging. Thanks to computers, Conlogue can unlock the secrets of the mummified woman without having to touch her. He x-rayed the skeleton and uploaded the information on his computer. From that, he was able to determine some insights about the mysterious woman.

12. They conducted a virtual autopsy

With 3D imaging, analysts could peel back the layers on the female’s remains. By doing so, they can see not just the skeleton, but also her internal organs. Her bones revealed the woman had a lot of strain on her lower back — likely the result of early onset of arthritis. The team deduced that the woman likely worked a labor intensive job that likely required her to bend over a lot.

Because her bones were fully fused, analysts confidently assumed the woman was an adult and had died at a relatively young age. They also estimated that the woman in question was between 25-35 years old, but probably no older than 30 years. Those weren’t the only things they found about the woman in the iron coffin.

Because her bones were fully fused, analysts confidently assumed the woman was an adult and had died at a relatively young age. They also estimated that the woman in question was between 25-35 years old, but probably no older than 30 years. Those weren’t the only things they found about the woman in the iron coffin.

13. The lesions were more than skin deep

Researchers also confirmed that the cause of the woman’s death was indeed smallpox. Upon further investigation, they determined the contagion was blistering. When smallpox blisters and opens, it leaves permanent scarring. That signified that the woman had endured a high fever and most likely entered a comatose state before her death.

The smallpox on her body was so severe that the lesions on her head penetrated her skull and reached the thin membrane around her brain cavity. They knew, with 100% certainty, that it was the pox that killed her. However, the question of her identity remained, as well as why she had been buried in an iron coffin.

14. Dolley Madison was buried in an iron coffin

Ten bucks says you didn’t know former First Lady, Dolley Madison, was buried in said iron coffin. they were manufactured by Almond Dunbar Fisk (imagine someone being named Almond?). Fisk was originally a stove manufacturer out of Lower Manhattan in 1844.

When his brother William Fisk passed away in Mississippi, Almond decided to do something revolutionary. At the time, where people died was the place they were most likely to be buried. To be transported from one state to another was logistically difficult, especially over long distances. The Fisk family were mourning, which prompted Almond Fisk to create something unusual.

15. Almond Fisk designed the iron coffin for transportation

Fisk bought a barn and created a foundry for his iron coffins. In 1848 he was granted a patent for his creation. Iron coffins were a means to transport a deceased loved one before the invention of modern embalming. The coffin was an airtight casket with a logo at the head and the name of the manufacturer and the year in the center.

The face of the coffin had a porthole that could swivel open and allowed for loved ones to see the deceased behind a pane glass window. Once the viewing was over, the window was closed and bolted, and the coffin was sent to wherever it needed to be sent. But iron was expensive, and a whole coffin made of it didn’t come cheap.

16. The coffins were not cheap

Iron coffins were an effective way to both preserve and transport bodies. However, they often had a high price tag. As such, they were most commonly bought by members of high society, including First Lady Dolly Madison. It was rare that a member of the working class would be able to make such a purchase.

So how did this working class woman end up in a coffin usually only accessible for the wealthy? The answer lied in a usually unknown part of history. Before Emancipation Proclamation in 1863, many Northeastern states were still slave states, including New York. However, in 1799, New York passed a new law that would change everything.

17. New York passed the Gradual Emancipation Act

An act known as the Gradual Emancipation Act was passed in 1799. It declared that any slave born after July 4, 1799 was free, while those born before July 4, 1799, were to remain slaves. It wasn’t until 1817 that a new law passed, freeing all slaves in the state. Even so, it wasn’t officially enacted until 1827.

Was the iron woman once a slave, brought to New York in the pursuit of freedom? How can we tell? Once again, we turn to scientists to peer into what was most likely a tumultuous life for the iron lady. To get more answers, scientists examined something that had a lot of answers: her teeth.

18. Was the Iron Lady racing toward freedom?

Our mystery lady was born somewhere in the early 1800s, this much is true. How do we know? Fisk’s coffins were manufactured between 1848-1850, and looking at the bones, the woman in question couldn’t have been older than her early thirties. The math and it places our mummy in the earlier part of the 19th century.

The next question was where she was born. Her teeth give the best answer. Teeth absorb the chemicals in the water we drink, and by analyzing the chemicals found in her molars, researchers were able to determine where in the US the woman in the iron coffin had lived during her life. The results were positive.

19. She was a true New Yorker

The chemicals found in her teeth matched the same chemical composition found in the water in the North East during the 19th century. The amount of lead found was higher than predicted, and those levels would most likely occur in urban settings, specifically in New York while industrialization was at its peak.

What she ate and drank was a reflection of how an average New Yorker lived. From a strand of her hair, scientists were able to determine where she might have lived and even what her diet consisted of. Where she was, and what she did in her day to day were integral parts of her identity. So, what did this discovery tell us about life in New York in the 1800s?

20. We’re not in Dutchland anymore

Queens has changed a lot since the mid-19th century, to say the least. Official city records reveal that Queens was made up several towns — two of which were Flushing and Newtown, the location where the iron coffin was discovered. It was a small place: a one-street town with nothing beyond.

As it turned out, the area where she was discovered used to be the side of an African American church, on what used to be called Dutch Lane. Once a primarily Dutch community, the land was later sold to an African American community. It was a stable African American community that shared religion, politics, and social communion. The iron lady likely was a member of this community.

21. They found a census report

After they bought it from the Dutch, the community organized the funds to build a communal place of worship and a plot for a cemetery. They also set up a fellowship aimed at providing support to community members in need.

However, record keeping at the time was, at best, spotty. Until 1850, there was no census that logged the African American population —  they did not yet have the right to vote. But researchers got lucky and discovered something truly serendipitous in the case of the lady in the iron coffin. They found a name in a census that could have belonged to the woman.

22. Her identity was found

The 1850 New York census was the first to include African Americans. There, researchers found a name that might very well belong to the lady in the iron coffin. Thirty-three candidates were chosen as potentials, but one stuck out to investigators: Martha Peterson. Martha Peterson was 26 years old in 1850, and lived with a man William Raymond.

William Raymond was iron coffin creator Almond Fisk’s brother-in-law, neighbor, and partner. Martha Peterson was the daughter of prominent members of Queen’s African American community — the same community where the mummified remains were found. Was the body in question that of Martha Peterson?

23. Their profiles matched almost perfectly

The fact that Martha was living with Raymond (the coffin maker’s brother-in-law) was significant because, as mentioned earlier, the cost of the iron coffins was prohibitively expensive. As investigators dug a little deeper, they found that Martha was part of a small-town, African American community that was well-respected and pious.

Like her community, Peterson must have been well-loved and respected, evident in what she wore and how she was laid to rest. Investigators now had a name and reason. Many would have closed the case after discovering Peterson’s identity. But investigators took things one step further. With her name revealed, it was time to give her a face. More science ensues.

24. Science helped reconstruct her face

A forensic specialist uses facial reconstruction software to put a face to the deceased. Their job is to help law enforcement identify victims that have no identity. Using a computer via CT scan, the re-constructionist looks at the skull to ascertain details about what the person’s facials features were like.

The skull helps the specialist determine facial features including the shape of their eyes, nose, and mouth, all of which are pieces of the facial puzzle. Because the iron lady was damaged upon her discovery, the first step was to repair the damage to the skull. Never having to touch the remains, specialists were able to reconstruct the skull using digital programs.

25. The face was like a puzzle

Once completed, the specialist added the muscles in her face. They build up those features, they sourced a database of skin tones, noses, and eye-shapes. Everything came together as a unified image, and soon, forensic artists were looking into a very life-like Martha Peterson’s face. It was all made possible by technology.

She was no longer the anonymous lady in the iron coffin; she now had a name and an identity. With that, investigators had an intimate connection to the person she once was and could have been. She was no longer an idea or a figure of the past.  Now, she was an individual who, like everyone else, was living her life day by day until her untimely death.

26. They gave her a proper burial

The mystery was solved. There was only one thing left to do, and that was to lay Martha to rest. But it wouldn’t be done unceremoniously. Though the African American church had moved from its original location where the body was discovered in 1929, the community still exists today. The members of the Saint Mark African Methodist Episcopal Church were contacted.

Upon hearing the discovery of Martha Peterson, the church was in a buzz of excitement. To the community, it was more than just identifying a mystery woman from 150 years prior. It was a connection to an important part of their past. 

27. A darker side to history

For many African Americans, life during the 19th century was lost to a lack of education, documentation, and literacy. To find Martha Peterson was to find a piece of their own history that was not well documented. What makes Peterson so significant to her community is that she represented an entire population of people.

She wasn’t a Harriet Tubman, or a Sojourner Truth, but a woman with an ordinary life. What was what many in the Queen’s community could connect with her on. She represented the early struggles, triumphs, and mundane lifestyle realized by those living during this transitional point in history.

28. Martha Peterson represented everyday people

When the congregation of Saint Mark’s African Methodist Episcopal Church received Peterson, they treated her like someone who was recently deceased. They took her body to a funeral home where she was placed in a new Mahogany coffin and received a proper funeral. “The woman found represents us,” said Pastor Kimberly L. Detherage.

“She was found in our African-American burial ground, and because of that, she is a member of our congregation. And as a member of our congregation, it was important for us to make sure that we treated her with the very, utmost respect, that her life and her body was not treated disrespectfully. But most of all, we paid homage to the person that we believed that she was.”

29. She was more than just an exhumed body

What Martha Peterson looked like was more than a superficial visualization of a woman who died. It gave a face to how she lived alongside her community. She represented the everyday minority struggle during a time when Americans were pleading for citizenship and the right to vote, and living in poverty.

Many didn’t just wear the physical and mental manacles of slavery, but wore the manacles of history. What we know about that experience in history is found in rare autobiographies of the past, such as Solomon Northup, a free man who was taken into what would be twelve years of slavery (the basis of the Oscar-sweeping film). Finding Martha Peterson was much more intimate.

30. Martha is a reminder to keep the past close

Martha Peterson is physical evidence of time too close to forget. It’s rewarding to shed light on the African American community and their contribution to New York in the 19th century, though it is hidden and unknown. Though there are no writings about her life, Martha Peterson’s remains wrote that story for her.

She stands to remind many of the past, for them to carry as they usher into the future. It’s important to know the history, because it can be a useful tool in contextualizing the presented and informing the future. As long as there are bones, it’s impossible to erase history. –History